DESeq2 and edgeR are complicated programs for identifying differential gene expression from high-throughput sequencing data. This is the first in a long series of videos that explains how these programs work.

This time on StatQuest, it’s back to basics. People don’t always understand p-values as well as they should. Some people even confuse them with probabilities. Let’s not make those mistakes. As always, I’ve got a simple, easy to understand explanation with lots of examples so you will remember the concepts for years to come.

Dudes! Don’t fall into p-value traps – they are trickier than you might expect. In this video I expose one particularly tempting p-value trap and how to avoid it using power calculations.