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# Statquest

## An epic journey through computational methods for molecular geneticists.

# StatQuest: One vs Two-Tailed P-values

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2 thoughts on “StatQuest: One vs Two-Tailed P-values”

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This is a great lesson. I have done some R functions for this, stacked histograms etc to simulate this 2 stage process and show where the p-values are coming from (left-tailed or 2-sided test). This type of problem pops up when there is a 2 stage procedure on the same data where the outcome of the first test determines the second procedure. e.g. performing post-hoc confidence intervals after rejecting the null in a preliminary test, so take caution as confidence levels may be a bit lower than you think, especially for small sample sizes. You might look at this in a future video.

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That’s a great idea! Thanks for sharing it with me. :)

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